Promising treatment with stem cells from umbilical cord blood

baby face

Infantile Cerebral Palsy Treated With Stem Cells

 A boy known as L.B. is the first child with infantile cerebral palsy to be successfully treated with stem cells from his own umbilical cord blood, according to the German doctors who performed the treatment.

In her May 25th Daily Mail article, Rachel Reilly reported that two-year-old L.B. went into cardiac arrest in November 2008. He was paralyzed, with severe brain damage, and remained in a vegetative state. With no known treatment for the cause of infantile cerebral palsy, doctors held out little hope that he would survive.

 

Dr. Arne Jensen of the Campus Clinic Gynaecology said that L.B.’s parents researched alternative therapies and contacted doctors at the clinic to determine whether their son could be treated using his stored umbilical cord blood.

 

In January 2009, nine weeks after the brain damage, Dr. Jensen’s team administered the prepared blood intravenously and studied L.B.’s recovery at 2, 5, 12, 24, 30 and 40 months after the brain injury.

 

The likelihood of surviving such severe brain damage and over 25 minutes of resuscitation is just six percent; months after suffering this brain damage, children who do survive generally display minimal signs of consciousness. But within two months, L.B.’s muscle spasticity lessened significantly and he could see, sit, smile and speak simple words. L.B. could eat on his own, walk with help and speak in four-word sentences by about 40 months after treatment.

 

Dr. Jensen and Professor Dr. Eckard Hamelmann of the Department of Paediatrics at the Catholic Hospital Bochum (University Clinic of the RUB) reported on the treatment in the Case Reports in Transplantation journal. Dr. Jensen said the doctors could not definitively state the reason for L.B.’s recovery based on these results but noted that it would be “very difficult to explain these remarkable effects by purely symptomatic treatment during active rehabilitation.”

“Our findings, along with those from a Korean study, dispel the long-held doubts about the effectiveness of the new therapy,” said Dr. Jensen. In March, Korean doctors reported that, in a controlled study of 100 children, they had successfully treated cerebral palsy with allogeneic cord blood for the first time.

Note that this treatment did not use embryonic stem cells but stem cells from the boy’s own umbilical cord blood.

 

This entry was posted in Stem Cell Research. Bookmark the permalink.

4 Responses to Promising treatment with stem cells from umbilical cord blood

  1. goran says:

    I have similar problem with my 2 years old. I did save his stem cells from his own umbilical cord blood. Can anybody direct me towards somebody in Europe who can perform similar procedure for my boy. Contact me via my e-mail directly; gtresic2@hotmail.co.uk

  2. We have performed stem cell transplantation from patient’s own bone marrow for 18 patients at Vinmec hospital in Vietnam (vinmec.org) with very promising outcomes. If you are interested, you can contact me via my email: liemnhp@hotmail.com. You can see my scientific activities by check : home-pubmed then use keywords: LIEM NT

  3. Kari kari says:

    I wants to know who where I can get the stem cell treatment done for daughter she is 8 yrs I did not save her umbilical cord at birth I didn’t anything about that at the time and our country do not do that as we don’t have that by law

  4. ActionLife says:

    The treatment described in the post used the child’s own umbilical cord blood. We cannot advise on other medical treatments. We suggest discussing the matter with your family physician.

Leave a Reply

Your email address will not be published. Required fields are marked *